RIPK1-IN-20
RIPK1-IN-20 has strong RIPK1 kinase inhibitory activity with an IC50 value of 59.8 nM. It can block TNFα-induced necroptosis in both human and mouse cells, with an EC50 ranging from 1.06 to 4.58 nM.
Product Specifications
CAS Number
3026543-19-8
Field of Research
Cell Biology, Signal Transduction
Smiles
O=C1NN=C (N) C=2C (=CN (C12) CC3 (C) COC3) C=4C=CC5=C (C4) CCN5C (=O) CC=6C=CC=C (OC (F) (F) F) C6
Molecular Formula
C28H26F3N5O4
Molecular Weight
553.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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