DHFR-IN-13

DHFR-IN-13 (Compd Hit8) is an active inhibitor of R. solani DHFR, with an IC50 of 10.2 μM. It selectively inhibits human DHFR with an IC50 of 227.7 μM. Additionally, DHFR-IN-13 functions as a fungicide, demonstrating high antifungal activity against R. solani, with an EC50 of 38.2 mg/L.