PDEδ autophagic degrader 1
PDEδ autophagic degrader 1 (compound 12c) is an autophagosome-tethering compound (ATTEC) and a potent autophagic degrader of PDEδ. This compound effectively reduces PDEδ protein levels through lysosome-mediated autophagy without affecting PDEδ mRNA expression. Additionally, PDEδ autophagic degrader 1 inhibits the growth of KRAS mutant pancreatic cancer cells.
Product Specifications
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery
Molecular Formula
C41H42Br2IN7O5
Storage Conditions
-20°C
Notes
For research use only.
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