Oxodipine
Oxodipine, a dihydropyridine-type calcium antagonist, inhibits KCl-induced aortic contraction in rabbits and reduces cardiac force in less potent rat ventricular test-paper contractions. In rat cultured neonatal ventricular myocytes, Oxodipine reduces L-type Ca currents (I) with an IC50 of 0.24 μM, and against T-type Ca currents (I) with an IC50 of 0.41 μM. Oxodipine causes constipation in mice and gingival hyperplasia in dogs[1][2][3][4][5][6].
Product Specifications
CAS Number
90729-41-2
UNSPSC
12352005
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease; Others
Assay Protocol
https://www.medchemexpress.com/oxodipine.html
Solubility
10 mM in DMSO
Smiles
CCOC(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC=CC3=C2OCO3)=O
Molecular Formula
C19H21NO6
Molecular Weight
359.37
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/2039), CF594 conjugate, 0.1mg/mL
Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF405S conjugate, 0.1mg/mL
