Thalidomide-4-NH-PEG1-COOH TFA
Thalidomide-4-NH-PEG1-COOH TFA is a conjugate of an E3 ligase ligand and linker, composed of Thalidomide and NH-PEG3-NH-Boc. It serves as a Cereblon? ligand, facilitating the recruitment of CRBN? protein. This compound is a crucial intermediate in the synthesis of PROTAC molecules designed based on CRBN.
Product Specifications
CAS Number
2140807-20-9
Field of Research
Immunology & Inflammation; Pharmacology & Drug Discovery; Cell Biology, Pharmacology & Drug Discovery
Smiles
O=C (O) CCOCCNC1=CC=CC=2C (=O) N (C (=O) C12) C3C (=O) NC (=O) CC3.O=C (O) C (F) (F) F
Molecular Formula
C20H20F3N3O9
Molecular Weight
503.38
Storage Conditions
-20°C
Notes
For research use only.
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