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Thalidomide-4-NH-PEG1-COOH TFA

Thalidomide-4-NH-PEG1-COOH TFA is a conjugate of an E3 ligase ligand and linker, composed of Thalidomide and NH-PEG3-NH-Boc. It serves as a Cereblon? ligand, facilitating the recruitment of CRBN? protein. This compound is a crucial intermediate in the synthesis of PROTAC molecules designed based on CRBN.

Product Specifications

CAS Number

2140807-20-9

Field of Research

Immunology & Inflammation; Pharmacology & Drug Discovery; Cell Biology, Pharmacology & Drug Discovery

Smiles

O=C (O) CCOCCNC1=CC=CC=2C (=O) N (C (=O) C12) C3C (=O) NC (=O) CC3.O=C (O) C (F) (F) F

Molecular Formula

C20H20F3N3O9

Molecular Weight

503.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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