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Cbl-b-IN-15

Cbl-b-IN-15 (compound 25) is an inhibitor of the RING finger E3 ubiquitin ligase Cbl, demonstrating an IC50 of 15 nM. Cbl-b refers to Casitas B-lineage Lymphoma proto-oncogene-b, which can inhibit the activation of T cells, natural killer (NK) cells, and B cells. Cbl-b-IN-15 can activate T cell function with an EC50 of 0.41 μM.

Product Specifications

Field of Research

Cancer Biology, Protein Biochemistry

Molecular Formula

C27H27N5O3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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