(Rac) -PROTAC PARP/EGFR ligand 1
(Rac) -PROTAC PARP/EGFR ligand 1 is a compound that includes ligands for target proteins PARP and EGFR, along with a PROTAC linker that recruits E3 ligases such as VHL, CRBN, MDM2, and IAP. It is utilized in the synthesis of PROTAC DP-C-4, a dual CRBN-based PROTAC designed for the concurrent degradation of EGFR and PARP.
Product Specifications
CAS Number
2935073-36-0
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Smiles
O=C1NN=C (C=2C=CC=CC12) CC3=CC=C (F) C (=C3) C (=O) N4CCN (C (=O) CCCCCNC (=O) C (NC (=O) CCCCCOC5=CC=6C (=NC=NC6NC7=CC=C (F) C (Cl) =C7) C=C5OC) COCC#C) CC4
Molecular Formula
C53H56ClF2N9O8
Molecular Weight
1020.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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