Amylmetacresol

Amylmetacresol is a phenolic compound with topical antibacterial and antiviral activity. Amylmetacresol works by destroying the protein structure of the virus surface or interfering with the function of the virus lipid membrane. Amylmetacresol inhibits the attachment and replication of respiratory viruses such as human Rhinovirus 1a and influenza virus A, without significant effect on viruses such as HRV8. Amylmetacresol is mainly applied topically to the throat to relieve viral sore throats. Amylmetacresol is more active against enveloped viruses than non-enveloped viruses[1][2].

Product Specifications

CAS Number

[1300-94-3]

UNSPSC

12352005

Hazard Statement

H302

Target

Bacterial; Enterovirus; Influenza Virus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/amylmetacresol.html

Concentration

10mM

Purity

98.89

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC1=CC(O)=C(C=C1)CCCCC

Molecular Formula

C12H18O

Molecular Weight

178.28

Precautions

H302

References & Citations

[1]Martina Morokutti-Kurz, et al. Amylmetacresol/2,4-dichlorobenzyl alcohol, hexylresorcinol, or carrageenan lozenges as active treatments for sore throat. Int J Gen Med. 2017 Feb 28;10:53-60.|[2]Gong T, et al. [Synergistic Antibacterial Activity of Berberine in Combination with Amylmetacresol Against Enterococcus faecalis in vitro]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2020 Nov;51 (6) :749-754. Chinese.