Anti-Hu CD158z Purified
CD158z (KIR3DL3) is one of killer cell inhibitory receptors. It has three extracellular immunoglobulin-like domains and a long cytoplasmic tail, which, however, contains only one ITIM. Like other KIRs, CD158z is highly polymorphic, but it seems that its immunoglobulin-like domains are quite conserved among high primates.
Product Specifications
Certification
RUO
Reactivity
Human
Immunogen
Human CD158z transfectants
Target Antigen
CD158z
Clone
CH21
Applications
FC (QC tested), IP
Concentration
1 mg/mL
Format
Purified
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
*Trundley AE, Hiby SE, Chang C, Sharkey AM, Santourlidis S, Uhrberg M, Trowsdale J, Moffett A: Molecular characterization of KIR3DL3. Immunogenetics 2006 Jan;57 (12) :904-16., URL: https://pubmed.ncbi.nlm.nih.gov/16391939/
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
The mouse monoclonal antibody CH21 recognizes an extracellular epitope of human CD158z (KIR3DL3), a transmembrane glycoprotein of killer cell inhibitory receptor family.
Applications Notes
Flow cytometry: Recommended dilution: 3-12 µg/ml
Isotype
Mouse IgG2a
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