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(S, R, S) -AHPC-Me-8-bromooctanoic acid

(S, R, S) -AHPC-Me-8-bromooctanoic acid is an E3 ligase ligand-linker conjugate, and can be used for synthesis of PROTAC CYP1B1 degrader-2.

Product Specifications

CAS Number

2638512-58-8

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/s-r-s-ahpc-me-8-bromooctanoic-acid.html

Smiles

CC(C)([C@@H](C(N1[C@H](C(N[C@H](C2=CC=C(C3=C(C)N=CS3)C=C2)C)=O)C[C@@H](O)C1)=O)NC(CCCCCCCBr)=O)C

Molecular Formula

C31H45BrN4O4S

Molecular Weight

649.68

References & Citations

[1]Yao X, et al. Development of novel N-aryl-2,4-bithiazole-2-amine-based CYP1B1 degraders for reversing drug resistance. Eur J Med Chem. 2024 Jun 5;272:116488.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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