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BMY-25368 (hydrochloride)

Product Specifications

UNSPSC Description

BMY-25368 hydrochloride is a histamine H2 receptor antagonist that acts as a gastric acid secretion inhibitor. BMY-25368 hydrochloride competitively antagonizes gastric secretion stimulated by histamine and also antagonizes gastric secretion stimulated by Pentagastrin (HY-A0261), Bethanechol (HY-B0406), and food[1].

Target Antigen

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/bmy-25368-hydrochloride.html

Purity

97.0

Smiles

O=C1C(C(NCCCOC2=CC=CC(CN3CCCCC3)=C2)=C1N)=O.Cl

Molecular Weight

379.88

References & Citations

[1]Cavanagh RL, et al. Effect of BMY-25368, a potent and long-acting histamine H2-receptor antagonist, on gastric secretion and aspirin-induced gastric lesions in the dog. Aliment Pharmacol Ther. 1989 Jun;3(3):299-313.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-19010A/BMY-25368-hydrochloride-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-19010A/BMY-25368-hydrochloride-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

86134-36-3

Available Sizes

Curated Selection

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