BMY-25368 (hydrochloride)
Product Specifications
UNSPSC Description
BMY-25368 hydrochloride is a histamine H2 receptor antagonist that acts as a gastric acid secretion inhibitor. BMY-25368 hydrochloride competitively antagonizes gastric secretion stimulated by histamine and also antagonizes gastric secretion stimulated by Pentagastrin (HY-A0261), Bethanechol (HY-B0406), and food[1].
Target Antigen
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bmy-25368-hydrochloride.html
Purity
97.0
Smiles
O=C1C(C(NCCCOC2=CC=CC(CN3CCCCC3)=C2)=C1N)=O.Cl
Molecular Weight
379.88
References & Citations
[1]Cavanagh RL, et al. Effect of BMY-25368, a potent and long-acting histamine H2-receptor antagonist, on gastric secretion and aspirin-induced gastric lesions in the dog. Aliment Pharmacol Ther. 1989 Jun;3(3):299-313.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-19010A/BMY-25368-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-19010A/BMY-25368-hydrochloride-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
86134-36-3
Available Sizes
Curated Selection
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