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Rhapontigenin (Standard)

Rhapontigenin (Standard) is the analytical standard of Rhapontigenin. This product is intended for research and analytical applications. Rhapontigenin is a natural analog of resveratrol with anticancer, antioxidant, antifungal and antibacterial activities. Rhapontigenin is amechanism-based, potent and selective cytochrome P450 1A1 inactivator (IC50 = 400 nM) . Rhapontigenin exhibits 400-fold and 23-fold selectivity for P450 1A1 over P450 1A2 and P450 1B1, respectively[1].

Product Specifications

CAS Number

500-65-2

UNSPSC

12352005

Target

Bacterial; Cytochrome P450; Fungal; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; Others

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/rhapontigenin-standard.html

Smiles

OC1=CC(/C=C/C2=CC=C(OC)C(O)=C2)=CC(O)=C1

Molecular Formula

C15H14O4

Molecular Weight

258.27

References & Citations

[1]Roupe KA, et al. Preparative enzymatic synthesis and HPLC analysis of rhapontigenin: applications to metabolism, pharmacokinetics and anti-cancer studies.J Pharm Pharm Sci. 2005 Aug 22;8 (3) :374-86.|[2]Yeh YH, et al. Rhapontigenin inhibits TGF-β-mediated epithelial‑mesenchymal transition via the PI3K/AKT/mTOR pathway and is not associated with HIF-1α degradation.Oncol Rep. 2016 May;35 (5) :2887-95.|[3]Park EK, et al. Antithrombotic and antiallergic activities of rhaponticin from Rhei Rhizoma are activated by human intestinal bacteria.Arch Pharm Res. 2002 Aug;25 (4) :528-33.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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