PF-03814735
PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.
Product Specifications
CAS Number
942487-16-3
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction
Smiles
CC (=O) NCC (=O) N1[C@H]2CC[C@@H]1c1cc (Nc3ncc (c (NC4CCC4) n3) C (F) (F) F) ccc21
Molecular Formula
C23H25F3N6O2
Molecular Weight
474.48
Storage Conditions
-20°C
Notes
For research use only.
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