TL033
TL033 forms a component of an antibody-drug conjugate (ADC) as a drug-linker conjugate. It comprises a linker and a bioactive small molecule toxin. TL033 can be conjugated with the Sacituzumab antibody (anti-Trop-2) to synthesize BT001021, which exhibits anticancer activity against various cancers, including breast cancer, non-small cell lung cancer (NSCLC), and gastric cancer.
Product Specifications
CAS Number
2356230-22-1
Smiles
O=C1N2C (C=3C (C2) =C (CCN (S (C) (=O) =O) C (C) C) C=4C (N3) =CC=CC4) =CC5=C1COC (=O) [C@]5 (OC (OCC6=CC=C (NC ([C@@H] (NC (COCC (NCCOCCOCCOCCOCCOCCOCCOCCOCCN7C=C (CNC (CCCC#CC=8C=NC (S (C) (=O) =O) =NC8) =O) N=N7) =O) =O) CCCCN) =O) C=C6) =O) CC
Molecular Formula
C76H103N13O23S2
Molecular Weight
1630.83
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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