STAT3-IN-44
STAT3-IN-44 is a potent STAT3 inhibitor with IC50 values of 1.84 μM (C6 cells) and 4.81 μM (A549 cells) . It inhibits the phosphorylation of STAT3, downregulates Bcl-2 expression, and upregulates Caspase-3 expression, thereby promoting late-stage apoptosis. STAT3-IN-44 effectively suppresses tumor cell proliferation and migration and is applicable in research on cancers such as glioma and lung cancer.
Product Specifications
Field of Research
Cancer Biology, Cell Biology, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology
Storage Conditions
-20°C
Notes
For research use only.
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