PI3Kδ-IN-24
PI3Kδ-IN-24 is a selective inhibitor of PI3Kδ with an IC50 value of 0.1 nM. It exhibits significant antiproliferative effects on cancer cell lines that overexpress PI3Kδ. PI3Kδ-IN-24 reduces p-AKT levels and induces cell cycle arrest and apoptosis in tumor cells. This compound is applicable for cancer research, particularly in diffuse large B-cell lymphoma (DLBCL) .
Product Specifications
CAS Number
3051829-20-7
Field of Research
Cell Biology, Signal Transduction
Smiles
N ([C@H] (C (=O) N1CCN (C) CC1) C) C=2C3=C (C=CC (=N3) C=4C=C (C (OC5=CC=CC=C5) =O) C (OC) =NC4) N=CN2
Molecular Formula
C28H29N7O4
Molecular Weight
527.57
Storage Conditions
-20°C
Notes
For research use only.
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