ITK-IN-6
ITK-IN-6 is a potent and selective ITK inhibitor (Kd = 387 nM) . It binds directly to the ITK kinase domain. This compound prevents the release of pro-inflammatory cytokines and the activation and differentiation of Th2 and Th17 cells. ITK-IN-6 improves asthma progression by reducing inflammatory cell infiltration, mucus production, and IgE generation. It significantly inhibits airway inflammation and is used in asthma research.
Product Specifications
CAS Number
2616666-32-9
Field of Research
Signal Transduction
Smiles
O=C (NC1=CC=C (O) C (=C1) NS (=O) (=O) C) C2=CC=C (C=C2) C=3C=CC=C (Cl) C3Cl
Molecular Formula
C20H16Cl2N2O4S
Molecular Weight
451.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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