ITK-IN-6
ITK-IN-6 is a potent and selective ITK inhibitor (Kd = 387 nM) . It binds directly to the ITK kinase domain. This compound prevents the release of pro-inflammatory cytokines and the activation and differentiation of Th2 and Th17 cells. ITK-IN-6 improves asthma progression by reducing inflammatory cell infiltration, mucus production, and IgE generation. It significantly inhibits airway inflammation and is used in asthma research.
Product Specifications
CAS Number
2616666-32-9
Field of Research
Signal Transduction
Smiles
O=C (NC1=CC=C (O) C (=C1) NS (=O) (=O) C) C2=CC=C (C=C2) C=3C=CC=C (Cl) C3Cl
Molecular Formula
C20H16Cl2N2O4S
Molecular Weight
451.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TL302652V 500 µL Each
PCDH11X Human shRNA Lentiviral Particle (Locus ID 27328)
Sign In for Pricing
View Details MBS6506570-01 0.1 mL
ZBTB16, CT (Zinc Finger And BTB Domain-containing Protein 16, Zinc Finger Protein PLZF, Promyelocytic Leukemia Zinc Finger Protein, Zinc Finger Protein 145, ZBTB16, PLZF, ZNF145) (MaxLight 405)
Sign In for Pricing
View Details MBS6506570-02 5x 0.1 mL
ZBTB16, CT (Zinc Finger And BTB Domain-containing Protein 16, Zinc Finger Protein PLZF, Promyelocytic Leukemia Zinc Finger Protein, Zinc Finger Protein 145, ZBTB16, PLZF, ZNF145) (MaxLight 405)
Sign In for Pricing
View Details 