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Z1609609733

Z1609609733 (Compound 18) is a non-covalent inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 1.46 μM. It effectively suppresses serine synthesis, interferes with cancer metabolism, and completely halts cell proliferation.

Product Specifications

CAS Number

2375374-15-3

Field of Research

Metabolism Research

Smiles

O=C (OC (OC (=O) C (C=1C=NC=CC1) C2=CC=C (C=C2) C3 (NC (=O) C4=CC=5C (Cl) =C (Cl) C=CC5N4C) COC3) C) C

Molecular Formula

C30H27Cl2N3O6

Molecular Weight

596.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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