STAT3/CAIX-IN-1
STAT3/CAIX-IN-1 is a dual-target inhibitor of STAT3 (Kd: 60.03 μM) and CAIX (IC50: 80.45 nM) . It induces ferroptosis by elevating reactive oxygen species (ROS) and lipid peroxides. This compound also inhibits cell migration, induces apoptosis, and causes cell cycle arrest in MDA-MB-231 cells. STAT3/CAIX-IN-1 is applicable for research in triple-negative breast cancer (TNBC) .
Product Specifications
CAS Number
3053583-60-8
Field of Research
Cancer Biology, Cell Biology, Immunology & Inflammation, Metabolism Research, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology
Smiles
C (=C\1/C (=O) \C (=C\C2=CC=C (C (F) (F) F) C=C2) \CN (C (CCCC (NC=3SC (S (N) (=O) =O) =NN3) =O) =O) C1) \C4=CC=C (C (F) (F) F) C=C4
Molecular Formula
C28H23F6N5O5S2
Molecular Weight
687.63
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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