ESC1002755
ESC1002755 is an inhibitor of 17β-HSD10 with an IC50 of 19 nM. Notably enzyme-specific, ESC1002755 exhibits non-competitive inhibition against the cofactor NADH. At a concentration of 50 μM, it shows minimal cytotoxicity in HEK293 cells. It holds potential for research in Alzheimer's disease and hormone-dependent cancers such as prostate, bone, and colorectal cancers.
Product Specifications
CAS Number
2915567-21-2
Field of Research
Metabolism Research
Smiles
C (=O) (N1[C@@H] (CCC1) C2=C (C=CC=C2) C3=CC (O) =CC=C3) C=4SC=CC4Cl
Molecular Formula
C21H18ClNO2S
Molecular Weight
383.89
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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