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ESC1002755

ESC1002755 is an inhibitor of 17β-HSD10 with an IC50 of 19 nM. Notably enzyme-specific, ESC1002755 exhibits non-competitive inhibition against the cofactor NADH. At a concentration of 50 μM, it shows minimal cytotoxicity in HEK293 cells. It holds potential for research in Alzheimer's disease and hormone-dependent cancers such as prostate, bone, and colorectal cancers.

Product Specifications

CAS Number

2915567-21-2

Field of Research

Metabolism Research

Smiles

C (=O) (N1[C@@H] (CCC1) C2=C (C=CC=C2) C3=CC (O) =CC=C3) C=4SC=CC4Cl

Molecular Formula

C21H18ClNO2S

Molecular Weight

383.89

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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