BMS-986470
BMS-986470 is a CRBN E3 ubiquitin ligase modulator (CELMoD) that activates fetal hemoglobin (HbF) . It is an orally available molecular glue degradator targeting ZBTB7A and WIZ protein degradation, thereby inducing gamma globin synthesis and activating HbF. It is applicable for studying sickle cell disease (SCD) .
Product Specifications
CAS Number
3036554-12-5
Field of Research
Pharmacology & Drug Discovery
Smiles
N (C1=C2C (C (=O) N (C2=O) [C@@H]3C (=O) NC (=O) CC3) =CC=C1) C4=C (C=C5C (=C4) N (C) C (=O) CC5) C=6C=C (C) N=CC6
Molecular Formula
C29H25N5O5
Molecular Weight
523.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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