PROTAC JAK1 degrader 1
PROTACJAK1 degrader 1 (compound 10c) is a potent and selective PROTAC JAK1 degrader with a DC50 of 214 nM. It also exhibits antitumor activity.
Product Specifications
CAS Number
3052553-20-2
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
N#CCNC (=O) C=1C=CC (=CC1) C2=NC (=NC=C2) NC3=CC=C (C=C3) N4CCC (C (=O) NCCCCC#CC5=CC=CC=6C (=O) N (C (=O) C56) C7C (=O) NC (=O) CC7) CC4
Molecular Formula
C44H41N9O6
Molecular Weight
791.85
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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