TLR7 agonist 22
TLR7 agonist22 (Compound 11a) is a selective TLR7 agonist with an IC50 value of 25.86 μM. It inhibits the secretion of cell HBsAg and effectively activates TLR7, inducing the release of TLR7-regulated cytokines IL-12, TNF-α, and IFN-α in human PBMC cells. TLR7 agonist22 shows promise for developing novel immunomodulatory drugs in HBV research.
Product Specifications
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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