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HAChE-IN-8

HAChE-IN-8 (Compound S-12) is an orally active and selective inhibitor of hAChE, with an IC50 of 0.486 μM. It also inhibits BACE-1 with an IC50 of 0.542 μM, but shows negligible inhibition of Dyrk1A (IC50>10 μM) . This compound reduces Aβ aggregation, exhibits good blood-brain barrier penetration, and is primarily used in Alzheimer's disease research.

Product Specifications

Field of Research

Cell Biology, Neuroscience, Signal Transduction

Molecular Formula

C25H22N4O4

Storage Conditions

-20°C

Notes

For research use only.

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