TGFβRII-IN-3
TGFβRII-IN-3 (Compound 2r) is a selective inhibitor of the TGFβ type II receptor (TGFβ RII) with an IC50 of 4.1 μM. It inhibits TGFβ signaling by promoting protein degradation of TGFβ RII. Additionally, TGFβRI-IN-7 can block the transition from endothelial to mesenchymal states and inhibit cell migration, making it useful for cancer research.
Product Specifications
CAS Number
2351149-20-5
Field of Research
Stem Cell & Developmental Biology
Smiles
O=C (C=1C=2C (=O) CC (C) (C) CC2NC1C) N (C) CC3=CC=CC (=C3) C4=CC=C (C=C4) C (F) (F) F
Molecular Formula
C27H27F3N2O2
Molecular Weight
468.51
Storage Conditions
-20°C
Notes
For research use only.
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