QC-182
QC-182 is a potent p300/CBP PROTAC degrader. It reduces p300 protein levels in SK-HEP-1 cells with a DC50 of 93 nM. QC-182 effectively inhibits cell growth in SK-HEP-1 and JHH7 cell lines, with IC50 values of 0.733 μM and 0.477 μM, respectively. QC-182 is applicable for hepatocellular carcinoma (HCC) research.
Product Specifications
CAS Number
3032646-96-8
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
O=C1N ([C@H] (C=2N (C=3C (N2) =CC (=CC3) C=4C (C) =NOC4C) C5CCN (CC5) C6CN (C6) C=7C=C8C (=CC7) C (=O) N (C8=O) C9C (=O) NC (=O) CC9) CCC1) C%10=CC (F) =C (F) C=C%10
Molecular Formula
C44H42F2N8O6
Molecular Weight
816.85
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
45351154 3x 1.0 µg DNA
Spna1 CRISPR All-in-one AAV vector set (with saCas9)(Mouse)
Sign In for Pricing
View Details 
GTR10467005 96 Well
Sheep Alpha tocopherol transfer protein like (TTPAL) ELISA kit
Sign In for Pricing
View Details 
MBS1406166-01 0.02 mg (E-Coli)
Recombinant Pseudomonas aeruginosa Cysteine synthase B (cysM)
Sign In for Pricing
View Details