HTRA1-IN-1
HTRA1-IN-1 (Compound 17) is a selective inhibitor of the serine protease high temperature requirement A serine peptidase 1 (HTRA1), with an IC50 of 13 nM. It shows potential for improving conditions related to HTRA1, such as age-related macular degeneration (AMD), osteoarthritis, and rheumatoid arthritis.
Product Specifications
CAS Number
3052552-04-9
Field of Research
Protein Biochemistry
Smiles
[C@H] (CC1=CC (Cl) =CC=C1) (C (N[C@H] (C (N[C@H] (B (O) O) C2CCC2) =O) CC (C) C) =O) NC (C (CC3=CC=CC=C3) (C) C) =O
Molecular Formula
C31H43BClN3O5
Molecular Weight
583.95
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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