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3-Methyl-2-quinoxalinecarboxylic acid

3-Methyl-2-quinoxalinecarboxylic acid (MQCA), an important N-oxide reductive metabolite of Quinocetone or Olaquindox, potently inhibits the growth of Chang liver cells through S phase arrest of the cell cycle[1].

Product Specifications

CAS Number

[74003-63-7]

Product Name Alternative

MQCA

UNSPSC

12352005

Hazard Statement

H302, H319, H335

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/3-methyl-2-quinoxalinecarboxylic-acid.html

Purity

97.65

Solubility

10 mM in DMSO

Smiles

O=C(C1=NC2=CC=CC=C2N=C1C)O

Molecular Formula

C10H8N2O2

Molecular Weight

188.18

Precautions

H302, H319, H335

References & Citations

[1]Keyu Zhang , et al. Cytotoxicity and Genotoxicity of 1,4-bisdesoxyquinocetone, 3-methylquinoxaline-2-carboxylic Acid (MQCA) in Human Hepatocytes. Res Vet Sci. 2012 Dec;93 (3) :1393-401.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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