3-Methyl-2-quinoxalinecarboxylic acid
3-Methyl-2-quinoxalinecarboxylic acid (MQCA), an important N-oxide reductive metabolite of Quinocetone or Olaquindox, potently inhibits the growth of Chang liver cells through S phase arrest of the cell cycle[1].
Product Specifications
CAS Number
[74003-63-7]
Product Name Alternative
MQCA
UNSPSC
12352005
Hazard Statement
H302, H319, H335
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-methyl-2-quinoxalinecarboxylic-acid.html
Purity
97.65
Solubility
10 mM in DMSO
Smiles
O=C(C1=NC2=CC=CC=C2N=C1C)O
Molecular Formula
C10H8N2O2
Molecular Weight
188.18
Precautions
H302, H319, H335
References & Citations
[1]Keyu Zhang , et al. Cytotoxicity and Genotoxicity of 1,4-bisdesoxyquinocetone, 3-methylquinoxaline-2-carboxylic Acid (MQCA) in Human Hepatocytes. Res Vet Sci. 2012 Dec;93 (3) :1393-401.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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