Otaplimastat HCl
Otaplimastat HCl is a matrix metalloproteinase (MMP) inhibitor that blocks NMDA receptor-mediated excitotoxicity competitively and exhibits antioxidant activity, In oxygen-glucose-deprived endothelial cells, otaplimastat suppressed the activity rather than protein expression of MMPs by restoring the level of tissue inhibitor of metalloproteinase (TIMP) suppressed in ischemia, and consequently reduced vascular permeation. serving as a tool for research into brain ischemic injury and neuroprotection.
Product Specifications
CAS Number
1176758-02-3
Field of Research
Neuroscience, Protein Biochemistry
Purity
100.00% (May vary between batches)
Smiles
Cl.O=C1NC=2C=CC=CC2C (=O) N1CCCNCCCCN (C (=O) C) CCCN3C (=O) NC=4C=CC=CC4C3=O
Molecular Formula
C28H35ClN6O5
Molecular Weight
571.07
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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