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Otaplimastat HCl

Otaplimastat HCl is a matrix metalloproteinase (MMP) inhibitor that blocks NMDA receptor-mediated excitotoxicity competitively and exhibits antioxidant activity, In oxygen-glucose-deprived endothelial cells, otaplimastat suppressed the activity rather than protein expression of MMPs by restoring the level of tissue inhibitor of metalloproteinase (TIMP) suppressed in ischemia, and consequently reduced vascular permeation. serving as a tool for research into brain ischemic injury and neuroprotection.

Product Specifications

CAS Number

1176758-02-3

Field of Research

Neuroscience, Protein Biochemistry

Purity

100.00% (May vary between batches)

Smiles

Cl.O=C1NC=2C=CC=CC2C (=O) N1CCCNCCCCN (C (=O) C) CCCN3C (=O) NC=4C=CC=CC4C3=O

Molecular Formula

C28H35ClN6O5

Molecular Weight

571.07

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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