ClpP modulator-1
ClpPmodulator-1 (Compound BC8a) is a peptide mimic functioning as an allosteric ClpP modulator. At low concentrations, ClpPmodulator-1 acts as a ClpP activator, with EC50 values of 0.35 μM for Neisseria meningitides ClpP (NmClpP) and 0.58 μM for Escherichia coli ClpP (EcClpP) . At higher concentrations, it inhibits peptidase activity by competitively blocking substrate protein (LY-AMC) binding to the ClpPC site. ClpPmodulator-1 exhibits antibacterial properties and is applicable in bacterial infection research.
Product Specifications
CAS Number
2363753-48-2
Field of Research
Protein Biochemistry
Smiles
[C@H] (C (N[C@@H] (CC (C) C) B (O) O) =O) (NC (=O) C1=C (Cl) C=C (OC) C=C1) CC (C) C
Molecular Formula
C19H30BClN2O5
Molecular Weight
412.72
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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