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VNRX-9945

VNRX-9945 is a potent and orally active HBV capsid assembly modulator (CAM), exhibiting an EC50 value of 2.6 nM. It demonstrates excellent and broad-spectrum antiviral activity against multiple HBV genotypes in vitro, with favorable pharmacokinetic properties across various species. Additionally, VNRX-9945 shows significant antiviral efficacy in the AAV-HBV infected mouse model.

Product Specifications

CAS Number

2396680-45-6

Field of Research

Infectious Disease & Virology

Smiles

C (C (N[C@@H]1CC[C@H] (O) CC1) =O) (=O) C2=C (C) C (C (NC3=CC (C) =C (F) C=C3) =O) =C (C) N2C

Molecular Formula

C23H28FN3O4

Molecular Weight

429.48

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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