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TK-684

TK-684 is a potent and selective allosteric inhibitor of SHP2, with IC50 values of 2.1 nM for SHP2WT and greater than 1000 nM for SHP2PTP. It inhibits cell proliferation and induces apoptosis (apoptosis) . Additionally, TK-684 reduces the protein expression of p-AKT and p-ERK.

Product Specifications

Field of Research

Cell Biology, Metabolism Research

Storage Conditions

-20°C

Notes

For research use only.

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