5α-Androstan-3α-ol
5α-Androstan-3α-ol is a γ-aminobutyric acid (GABA) receptor agonist. It inhibits the transcriptional activity of the orphan nuclear receptor CAR (constitutive androstane receptor) . By binding to CAR and promoting its dissociation from coactivator proteins, 5α-Androstan-3α-ol negatively regulates CAR's activity. This compound is useful for studying hormone metabolism and drug detoxification mechanisms mediated by nuclear receptors.
Product Specifications
CAS Number
7657-50-3
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
C[C@@]12[C@@]3 ([C@] ([C@]4 ([C@] (C) (CC3) CCC4) [H]) (CC[C@]1 (C[C@H] (O) CC2) [H]) [H]) [H]
Molecular Formula
C19H32O
Molecular Weight
276.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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