2-Methylthio isopentenyladenosine

2-Methylthio isopentenyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

CAS Number

[20859-00-1]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/2-methylthio-isopentenyladenosine.html

Solubility

10 mM in DMSO

Smiles

O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N(C=N2)C3=C2C(NC/C=C(C)/C)=NC(SC)=N3

Molecular Formula

C16H23N5O4S

Molecular Weight

381.45

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26 (6) :1490-1500.|[2]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.