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Antibacterial agent 187

Antibacterial agent 187 (IKE7) is a derivative containing imidazole and triazolacridone structures that target yeast topoisomerase II. Antibacterial agent 187 has antifungal activity and MIC value of resistance to fluconazole (HY-B0101) is 32-64 μg/mL[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Fungal; Topoisomerase

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antibacterial-agent-187.html

Solubility

10 mM in DMSO

Smiles

N[C@@H](CCCCNCCCNC(C=CC1=C2N(N=N1)C3=C4C=C(OC)C=C3)=C2C4=O)C(N)=O

Molecular Formula

C23H29N7O3

Molecular Weight

451.52

References & Citations

[1]Rząd K, et al. Targeting yeast topoisomerase II by imidazo and triazoloacridinone derivatives resulting in their antifungal activity. Sci Rep. 2024 Feb 13;14 (1) :3594.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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