Antibacterial agent 187
Antibacterial agent 187 (IKE7) is a derivative containing imidazole and triazolacridone structures that target yeast topoisomerase II. Antibacterial agent 187 has antifungal activity and MIC value of resistance to fluconazole is 32-64 μg/mL[1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352005
Target
Fungal; Topoisomerase
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-187.html
Solubility
10 mM in DMSO
Smiles
N[C@@H](CCCCNCCCNC(C=CC1=C2N(N=N1)C3=C4C=C(OC)C=C3)=C2C4=O)C(N)=O
Molecular Formula
C23H29N7O3
Molecular Weight
451.52
References & Citations
[1]Rząd K, et al. Targeting yeast topoisomerase II by imidazo and triazoloacridinone derivatives resulting in their antifungal activity. Sci Rep. 2024 Feb 13;14 (1) :3594.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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