Uridine 5′-diphosphoglucose (Standard)

Uridine 5′-diphosphoglucose (Standard) (UDP-D-Glucose (Standard) ) is the analytical standard of Uridine 5′-diphosphoglucose (HY-113044) . This product is intended for research and analytical applications. Uridine 5’-diphosphoglucose (UDP-glucose), secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory P2Y14 receptor. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Uridine 5’-diphosphoglucose is also the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine 5’-diphosphoglucose is promising for research in counteracting myocardial infarction/reperfusion (MIR) -induced inflammation in the heart tissue.

Product Specifications

CAS Number

[133-89-1]

Product Name Alternative

UDP-D-Glucose (Standard)

UNSPSC

12352005

Hazard Statement

H302, H312, H315, H319

Target

Endogenous Metabolite; P2Y Receptor; Reference Standards

Type

Reference Standards

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease; Others

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/uridine-diphosphate-glucose-standard.html

Purity

99.59

Smiles

O[C@@H]1[C@H](O)[C@@H](COP(O)(OP(O)(O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)=O)=O)O[C@H]1N3C=CC(NC3=O)=O

Molecular Formula

C15H24N2O17P2

Molecular Weight

566.30

Precautions

H302, H312, H315, H319

References & Citations

[1]DietrichKeppler, et al. Uridine-5′-diphosphoglucose. Methods of Enzymatic Analysis (Second English Edition) . 1974;4:2225-2228.|[2]Das A, et al. Human P2Y (14) receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups. J Med Chem. 2010 Jan 14;53 (1) :471-80.