Dac590
Dac590 is an orally active FTO inhibitor. Dac590 has a robust antiproliferative effect on AML cells, and induces apoptosis and cell cycle G1 arrest by inhibiting oncogenic FTO signaling. Dac590 significantly inhibits tumor growth and prolongs survival with no observed toxicity in acute myeloid leukemia (AML) xenograft mcie model, and shows a synergistic effect combined with Decitabine (HY-A0004) .
Product Specifications
CAS Number
3084407-00-8
Purity
>98%
Smiles
OC (C1=CC (OC) =CC=C1NC2=C (C=C (C=C2Cl) C3=C (ON=C3C) C) F) =O
Molecular Formula
C19H16ClFN2O4
Molecular Weight
390.79
Notes
For research use only.
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