CYM 5442 hydrochloride
CYM5442 hydrochloride is a potent, highly-selective and orally active sphingosine 1-phosphate (S1P1) receptor agonist with an EC50 of 1.35 nM. CYM5442 hydrochloride is inactive against S1P2, S1P3, S1P4, and S1P5. CYM5442 hydrochloride activates S1P1-dependent p42/p44-MAPK phosphorylation. CYM5442 exerts retinal neuroprotection. CYM5442 hydrochloride can easily penetrate the central nervous system (CNS) .
Product Specifications
CAS Number
1783987-80-3
Purity
>98%
Smiles
Cl.O1C (C2C=CC (=C (C=2) OCC) OCC) =NC (C2=CC=CC3=C2CCC3NCCO) =N1
Molecular Formula
C23H28CLN3O4
Molecular Weight
445.939125061035
Notes
For research use only.
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