GSK717
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP) -induced NOD2-mediated signaling, with an IC50 of 400 nM for MDP-stimulated IL-8 secretion in HEK293/hNOD2 cells.
Product Specifications
CAS Number
1595278-21-9
Smiles
O=C (CN1C2C=CC=CC=2N=C1CCN (C (C1C=CC=CC=1) =O) C) NC1C=CC2=C (C=1) CCC2
Molecular Formula
C28H28N4O2
Molecular Weight
452.547526359558
Notes
For research use only.
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