AC3573
AC3573 (AC-3573) is a potent, specific small molecule inhibitor of HER3.AC3573 abrogates HER2–HER3 signalling in cells and is more specific for HER3, inhibits NRG (heregulin) -induced HER3 phosphorylation with IC50 of 10 uM, abrogates the formation of the active HER2-HER3 heterodimer, inhibits oncogenic downstream signalling in SK-BR-3 breast cancer cells.
Product Specifications
Purity
>98%
Molecular Formula
C18H15N5O2S
Molecular Weight
365.411
Notes
For research use only.
More Discoveries
Explore Other Products
Browse additional items from our catalog
H00011117-P01-10ug 10 µg
Recombinant Human EMILIN1 Protein - (Dry Ice)
Sign In for Pricing
View Details abx065060-01 10 µg
Human A Disintegrin And Metalloprotease 20 (ADAM20) Protein
Sign In for Pricing
View Details abx065060-02 50 µg
Human A Disintegrin And Metalloprotease 20 (ADAM20) Protein
Sign In for Pricing
View Details 
abx065060-03 100 µg
Human A Disintegrin And Metalloprotease 20 (ADAM20) Protein
Sign In for Pricing
View Details 
abx065060-04 200 µg
Human A Disintegrin And Metalloprotease 20 (ADAM20) Protein
Sign In for Pricing
View Details 
abx065060-05 500 µg
Human A Disintegrin And Metalloprotease 20 (ADAM20) Protein
Sign In for Pricing
View Details