P56Dok-2 (phospho-Tyr351) rabbit pAb
Docking protein 2 (DOK2) Homo sapiens The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Docking protein 2 (DOK2) Homo sapiens The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008]
UniProt
O60496
Swiss Prot
O60496
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized phosho peptide around human p56Dok-2 (Tyr351)
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:1000-2000
Molecular Weight
48kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
48kD
Fragment
IgG
Subcellular Location
Cytosol
Other Product Names
Docking protein 2 (Downstream of tyrosine kinase 2) (p56 (dok-2) )
Gene ID (Human)
9046
Available Sizes
Curated Selection
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