SD-436
SD-436 is a highly potent and selective STAT3 degrader with DC50 of 0.1 nM in human PBMCs and displays >10,000-fold degradation selectivity for STAT3 over other STAT proteins.
Product Specifications
CAS Number
2497585-50-7
Purity
0.98
Smiles
O=C1[C@H] (CN (CC[C@@H]2N1[C@@H] (CC2) C (N[C@@H] (CCC (N) =O) C (N[C@H] (C (N3CCC (CC3) CCC#CC4=CC=CC5=C4CN (C5=O) C6CCC (NC6=O) =O) =O) CC7=CC=C (C (F) =C7) F) =O) =O) C (OC) =O) NC (C8=CC9=C (S8) C=CC (C (F) (P (O) (O) =O) F) =C9) =O
Molecular Formula
C58H62F4N9O14PS
Molecular Weight
1248.2
Notes
For research use only.
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