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GNE-0011

GNE-0011 is a monovalent, JQ1-based BRD4 degrader that is not linked to an E3 ligase binder, triggers proteasomal and ubiquitin-dependent selective degradation of BRD4 over BRD2 and BRD3.

Product Specifications

CAS Number

2413382-30-4

Purity

0.98

Smiles

C12SC (C) =C (C) C=1C (C1=CC=C (C#CCN) C=C1) =N[C@@H] (CC (=O) OC (C) (C) C) C1=NN=C (C) N12

Molecular Formula

C26H29N5O2S

Molecular Weight

475.61

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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