GNE-0011
GNE-0011 is a monovalent, JQ1-based BRD4 degrader that is not linked to an E3 ligase binder, triggers proteasomal and ubiquitin-dependent selective degradation of BRD4 over BRD2 and BRD3.
Product Specifications
CAS Number
2413382-30-4
Purity
0.98
Smiles
C12SC (C) =C (C) C=1C (C1=CC=C (C#CCN) C=C1) =N[C@@H] (CC (=O) OC (C) (C) C) C1=NN=C (C) N12
Molecular Formula
C26H29N5O2S
Molecular Weight
475.61
Notes
For research use only.
Available Sizes
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