Zabofloxacin (hydrochloride)
Zabofloxacin hydrochloride (DW-224a) is a potent and seletive inhibitor of the bacterial type II and IV topoisomerases. Zabofloxacin hydrochloride has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia. Zabofloxacin hydrochloride is a novel fluoronaphthyridone quinolone that is considered as an alternative antibiotic for treatment of quinolone-susceptible (QSSP) and quinolone-resistant gonorrhea (QRSP) [1].
Product Specifications
CAS Number
[623574-00-5]
Product Name Alternative
DW-224a
UNSPSC
12352005
Target
Antibiotic; Bacterial; Topoisomerase
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/zabofloxacin-hydrochloride.html
Purity
99.54
Solubility
DMSO : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)C1=CN(C2=NC(N(CC/34CNC4)CC3=N\OC)=C(C=C2C1=O)F)C5CC5.[H]Cl
Molecular Formula
C19H21ClFN5O4
Molecular Weight
437.85
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
Quinolone; Topo I; Topo II
Available Sizes
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